We do not create mechanical prosthetics or develop heavy exoskeletons. Instead, we take a different path — we awaken the body’s own neural networks that remain intact even after severe spinal cord injuries, stroke, or in cases of cerebral palsy.
A Russian Technology Helping Spinal Cord Injury Patients Get Back on Their Feet
Scientific Foundation
Academic School
СOSIMA emerged from years of research conducted at the Pavlov Institute of Physiology of the Russian Academy of Sciences — one of the oldest and most authoritative scientific institutions in the country in the field of neurophysiology.
Learn More СOSIMA emerged from years of research conducted at the Pavlov Institute of Physiology of the Russian Academy of Sciences — one of the oldest and most authoritative scientific institutions in the country in the field of neurophysiology.
Tomorrow
Today
We create a new standard of highly efficient and affordable rehabilitation
Yesterday
Together we accomplish your dream
A group of Russian neurophysiologists led by Yu. P. Gerasimenko has developed a non-invasive technique for restoring movements for patients with spinal cord injury.
The technique is based on a breakthrough technology of non-invasive neurostimulation of the spinal cord.
The technique is based on a breakthrough technology of non-invasive neurostimulation of the spinal cord.
A new strategy of Neurorehabilitation
We have learned not only to start the movement of the affected function, but also to control it. Multilevel spinal cord stimulation combined with locomotor training is the basis of the new strategy.
From habilitation to rehabilitation
The latest results of researches of our team give every reason to believe in the possibility of restoring motor function, not replacing it with prostheses, exoskeletons or wheelchairs. The trend is turning from habilitation to rehabilitation. That will dramatically change the lives of millions of patients with SCI and cerebral palsy.
Tomorrow
Today
We create a new standard of highly efficient and affordable rehabilitation
Yesterday
Together we accomplish your dream
A group of Russian neurophysiologists led by Yu. P. Gerasimenko has developed a non-invasive technique for restoring movements for patients with spinal cord injury.
The technique is based on a breakthrough technology of non-invasive neurostimulation of the spinal cord.
The technique is based on a breakthrough technology of non-invasive neurostimulation of the spinal cord.
A new strategy for neurorehabilitation
We have learned not only to start the movement of the affected function, but also to control it. Multilevel spinal cord stimulation combined with locomotor training is the basis of the new strategy.
From habilitation to rehabilitation
The latest results of researches of our team give every reason to believe in the possibility of restoring motor function, not replacing it with prostheses, exoskeletons or wheelchairs. The trend is turning from habilitation to rehabilitation. That will dramatically change the lives of millions of patients with SCI and cerebral palsy.
Meet Our Team
COSIMA is a Russian scientific and manufacturing company that brings together neurophysiologists, engineers, and clinicians with a single goal: to help paralyzed individuals regain the ability to move independently.
We do not create mechanical prosthetics or develop heavy exoskeletons. Instead, we take a different approach — we awaken the body’s own neural networks, which remain intact even after severe spinal cord injuries, strokes, or cerebral palsy.
Founded in 2010 in Moscow, COSIMA has since become a resident of the Skolkovo Biomedical Cluster. Over the years, we have progressed from fundamental scientific research to the serial production of medical devices, which are now in operation at leading rehabilitation centers in Russia.
Learn More We do not create mechanical prosthetics or develop heavy exoskeletons. Instead, we take a different approach — we awaken the body’s own neural networks, which remain intact even after severe spinal cord injuries, strokes, or cerebral palsy.
Founded in 2010 in Moscow, COSIMA has since become a resident of the Skolkovo Biomedical Cluster. Over the years, we have progressed from fundamental scientific research to the serial production of medical devices, which are now in operation at leading rehabilitation centers in Russia.
- 20 yearsof fundamental and clinical research — making movement restoration possible without surgery
- 500,000 Peopleface spinal cord injuries each year — and gain a chance to restore function
- from 70% to 36%the share of patients completely dependent on assistance decreases
- 70%patients achieve their individual functional rehabilitation goals
- 98,3%patients show a motor response to stimulation, confirming the high reproducibility of the method
- 130+scientific publications
10%
have access to efficient rehabilitation technologies
In total
Only 10%
Only 10%
Making our best to help patients with SCI and cerebral palsy all around the globe
badly need
motor rehabilitation
motor rehabilitation
18 million people
Making our best to help patients with SCI and cerebral palsy all around the globe
10%
have access to efficient
rehabilitation technologies
rehabilitation technologies
In total
Only 10%
Only 10%
badly need
motor rehabilitation
motor rehabilitation
18 million people
Making our best to help patients with SCI and cerebral palsy all around the globe
10%
have access to efficient
rehabilitation technologies
rehabilitation technologies
In total
Only 10%
Only 10%
badly need
motor rehabilitation
motor rehabilitation
18 million people
Global strategy of neurorehabilitation
The new neurorehabilitation approach gives us hope for the restoration of not only motor, but also visceral functions, allowing us to target the areas of the spinal cord responsible for respiratory, cardiovascular and genitourinary functions.
Recent clinical studies on patients with cerebral palsy and after a stroke have shown a significant improvement in the quality of walking in these categories of patients.
Of course, we are still at the beginning of the journey, but the first results of experimental clinical studies allow us to say with confidence that we are moving in the right direction. The question of scaling these results is only a matter of time and financial possibilities.
Global strategy of neurorehabilitation
The new neurorehabilitation approach gives us hope for the restoration of not only motor, but also visceral functions, allowing us to target the areas of the spinal cord responsible for respiratory, cardiovascular and genitourinary functions.
Recent clinical studies on patients with cerebral palsy and after a stroke have shown a significant improvement in the quality of walking in these categories of patients.
Of course, we are still at the beginning of the journey, but the first results of experimental clinical studies allow us to say with confidence that we are moving in the right direction. The question of scaling these results is only a matter of time and financial possibilities.
Just take a look how we use our devices
Leadership
- Yuri GerasimenkoScientific Director
- Sergey ChernoutsanManaging Director
- Alexander GrishinChief of R&D Department
- Sergey SolovevTechnical Director
- Yulia PetrovaFinancial Director
- Sergey YatsenkoMarketing Director (CMO)
- Alexander YudinHead of Sales
- Pavel UshakovChief of Quality Control Department
- Yuri GerasimenkoScientific Director
- Sergey ChernoutsanManaging Director
- Alexander GrishinChief of R&D Department
- Sergey SolovevTechnical Director
- Yulia PetrovaFinancial Director
- Sergey YatsenkoMarketing Director (CMO)
- Alexander YudinHead of Sales
- Pavel UshakovChief of Quality Control Department
Equipment
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NeoStim‑C.5
NeoStim‑C.5 is designed for transcutaneous electrical stimulation of the spinal cord through five independent channels, aimed at correcting and restoring motor and visceral functions.
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NeoStim‑C.6
The device is intended for continuous and rhythmic transcutaneous electrical stimulation of the cervical and lumbar enlargements, as well as the dorsal roots of the spinal cord, to correct and restore motor functions. -
NeoStim‑16
The myostimulator is designed to correct and restore motor functions, as well as provide analgesia in painful areas during patient movement, using transcutaneous electrical myostimulation. -
Spinal Neuroprosthesis
The device is designed for continuous and rhythmic transcutaneous electrical stimulation of the cervical and lumbar enlargements, as well as the dorsal roots of the spinal cord, using an electrode matrix to correct and restore motor functions. -
BiosKin‑ES APC
The hardware-software complex is designed for locomotor-type mechanotherapy of the upper and lower limbs, combined with transcutaneous spinal cord stimulation or myostimulation, to correct and restore motor functions.
NeoStim-5
Multisite Transcutaneous Spinal Stimulation for Walking and Autonomic Recovery - Scientific Device
Basic principles:
Multisite transcutaneous spinal stimulation induces neuroplasticity of the spinal networks.
Field of application:
NeoStim-5 is a scientific device. It can be used for research purposes only for noninvasive stimulation of the nervous system including spinal cord (neural networks and spinal pathways), dorsal and ventral roots as well as peripheral nerves.
It can help understand how changes in connectivity in the nervous system/spinal cord are related to training exercises performed by individuals with motor disorders after a stroke, spinal cord injury, child cerebral palsy, sports and military trauma, aggravation of neurologic symptoms after surgical manipulations on the spine and peripheral neuromuscular apparatus.
It cannot be used in any conditions as a medical device for any clinical trials or as a marketed product for any commercialization efforts.
Basic principles:
Multisite transcutaneous spinal stimulation induces neuroplasticity of the spinal networks.
Field of application:
NeoStim-5 is a scientific device. It can be used for research purposes only for noninvasive stimulation of the nervous system including spinal cord (neural networks and spinal pathways), dorsal and ventral roots as well as peripheral nerves.
It can help understand how changes in connectivity in the nervous system/spinal cord are related to training exercises performed by individuals with motor disorders after a stroke, spinal cord injury, child cerebral palsy, sports and military trauma, aggravation of neurologic symptoms after surgical manipulations on the spine and peripheral neuromuscular apparatus.
It cannot be used in any conditions as a medical device for any clinical trials or as a marketed product for any commercialization efforts.
NeoStim-3
Multisite Transcutaneous Spinal Stimulation for Walking and Autonomic Recovery
Basic principles:
Multisite transcutaneous spinal stimulation induces neuroplasticity of the spinal networks.
Field of application:
Non-invasive electrical SCS is the cornerstone of an innovative technology for motor rehabilitation of paralyzed patients with spinal cord injury, cerebral palsy and after a stroke, based on fundamental physiological researches.
Functional possibilities:
- Recovery of locomotor and autonomic functions in people with chronic SCI
- Improved muscle sensation and bowel function
- Reduction of spasticity and improvement of walking coordination
- Improvement of genitourinary function
NeoStim-16
Transcutaneous functional electrical stimulation (FES) for the correction of pathological motor stereotypes
Basic principles:
Percutaneous effect of electrical impulses on muscles and peripheral nerves, which coincides with periods of their natural activity during cyclic movements.
Field of application:
An effective way to correct pathological motor stereotypes after a stroke, cerebral palsy. Method is increasingly popular in sports medicine. Stimulation is carried out during cyclic movements of the patient: walking, cycling, elementary cyclic movements (flexion-extension of the limbs).
Functional possibilities:
- Restoration of the correct walking stereotype
- Restoration of muscle sensitivity
- Improvement in genitourinary function
- Reduction of spasticity and improvement of walking coordination
Spinal Neuroprosthesis
Portable device for independent walking after a stroke
Basic principles:
Movement occurs not due to artificial orthoses, but due to the patient's own muscles, reinforced by multilevel non-invasive stimulation of the spinal cord. The electrode matrix allows you to stimulate not only the spinal cord itself, but also the roots of the spinal cord with intermittent pulses at the same time with the stimulation of the cervical region with direct current.
Field of application:
Home rehabilitation, clinics, rehabilitation centers.
Advantages:
- Light portable device
- Real neurorehabilitation + real walking
- Much cheaper and more efficient than exoskeletons: movement occurs due to the patient's own muscles, and not due to artificial orthoses
Patents
Publications
Effect of epidural stimulation of the lumbosacral spinal cord on voluntary movement, standing, and assisted stepping after motor complete paraplegia
Engaging cervical spinal circuitry with non-invasive spinal stimulation and buspirone to restore hand function in chronic motor complete patients
Electrical Spinal Stimulation, and Imagining of Lower Limb Movements to Modulate Brain-Spinal Connectomes That Control Locomotor-Like Behavior
Initiation and modulation of locomotor circuitry output with multisite transcutaneous electrical stimulation of the spinal cord in noninjured humans
Noninvasive spinal stimulation safely enables upright posture in children with spinal cord injury
Utility and Feasibility of Transcutaneous Spinal Cord Stimulation for Patients With Incomplete SCI in Therapeutic Settings
Integration of sensory, spinal, and volitional descending inputs in regulation of human locomotion
Neuromodulation of lumbosacral spinal networks enables independent stepping after complete paraplegia
Collaborations
- Sestroretsk, Russia
- Moscow, Russia
- St. Petersburg, Russia
- St. Petersburg, Russia
- Cheboksary, Russia
- Ulyanovsk, Russia
- Barcelona, Spain
- Los Angeles, USA
- East Hanover, USA
- Miami, USA
